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Toll-Like Receptor 3 Signaling on Macrophages Is Required for Survival Following Coxsackievirus B4 Infection

Toll-like receptor 3 (TLR3) has been proposed to play a central role in the early recognition of viruses by sensing double stranded RNA, a common intermediate of viral replication. However, several reports have demonstrated that TLR3 signaling is either dispensable or even harmful following infectio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Richer, Martin J., Lavallée, Danielle J., Shanina, Iryna, Horwitz, Marc S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606033/
https://ncbi.nlm.nih.gov/pubmed/19122812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004127
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