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Predicting Novel Features of Toll-Like Receptor 3 Signaling in Macrophages
The Toll-like receptor (TLR) 3 plays a critical role in mammalian innate immune response against viral attacks by recognizing double-stranded RNA (dsRNA) or its synthetic analog polyinosinic-polycytidylic acid (poly (I∶C)). This leads to the activation of MAP kinases and NF-κB which results in the i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2645505/ https://ncbi.nlm.nih.gov/pubmed/19252739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004661 |
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