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Predicting Novel Features of Toll-Like Receptor 3 Signaling in Macrophages

The Toll-like receptor (TLR) 3 plays a critical role in mammalian innate immune response against viral attacks by recognizing double-stranded RNA (dsRNA) or its synthetic analog polyinosinic-polycytidylic acid (poly (I∶C)). This leads to the activation of MAP kinases and NF-κB which results in the i...

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Main Authors: Helmy, Mohamed, Gohda, Jin, Inoue, Jun-ichiro, Tomita, Masaru, Tsuchiya, Masa, Selvarajoo, Kumar
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645505/
https://ncbi.nlm.nih.gov/pubmed/19252739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004661
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