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Sequential Immunizations with heterosubtypic virus-like particles elicit cross protection against divergent influenza A viruses in mice

Seasonal influenza vaccines have proven to be effective against well-matched viruses in healthy adults. However, rapid accumulation of mutations in the main antigenic surface proteins of influenza can compromise the efficiency of flu vaccines. Occasionally, influenza pandemics arise and present a di...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Luo, Yuan, Mohan, Teena, Zhu, Wandi, Wang, Chao, Deng, Lei, Wang, Bao-Zhong
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854580/
https://ncbi.nlm.nih.gov/pubmed/29545521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22874-w
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