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Heterosubtypic influenza protection elicited by double-layered polypeptide nanoparticles in mice

Influenza is a persistent threat to public health. Here we report that double-layered peptide nanoparticles induced robust specific immunity and protected mice against heterosubtypic influenza A virus challenges. We fabricated the nanoparticles by desolvating a composite peptide of tandem copies of...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Proc Natl Acad Sci U S A
मुख्य लेखकों: Deng, Lei, Chang, Timothy Z., Wang, Ye, Li, Song, Wang, Shelly, Matsuyama, Shingo, Yu, Guoying, Compans, Richard W., Li, Jian-Dong, Prausnitz, Mark R., Champion, Julie A., Wang, Bao-Zhong
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099848/
https://ncbi.nlm.nih.gov/pubmed/30065113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805713115
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