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Virus-Like Particles Containing the Tetrameric Ectodomain of Influenza Matrix Protein 2 and Flagellin Induce Heterosubtypic Protection in Mice

The ectodomain of matrix protein 2 (M2e) is highly conserved among influenza A viruses and can be a promising candidate antigen for a broadly cross-protective vaccine. In this study, a tetrameric M2e (tM2e) and a truncated form of flagellin (tFliC) were coincorporated into virus-like particles (VLPs...

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Detalhes bibliográficos
Main Authors: Li Wang, Ying-Chun Wang, Hao Feng, Tamanna Ahmed, Richard W. Compans, Bao-Zhong Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2013-01-01
Colecção:BioMed Research International
Acesso em linha:http://dx.doi.org/10.1155/2013/686549
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