Enhanced Influenza Virus-Like Particle Vaccines Containing the Extracellular Domain of Matrix Protein 2 and a Toll-Like Receptor Ligand

The extracellular domain of matrix protein 2 (M2e) is conserved among influenza A viruses. The goal of this project is to develop enhanced influenza vaccines with broad protective efficacy using the M2e antigen. We designed a membrane-anchored fusion protein by replacing the hyperimmunogenic region...

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Detalhes bibliográficos
Main Authors: Wang, Bao-Zhong, Gill, Harvinder S., Kang, Sang-Moo, Wang, Li, Wang, Ying-Chun, Vassilieva, Elena V., Compans, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416094/
https://ncbi.nlm.nih.gov/pubmed/22647270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00153-12
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