Virus-Like Particles Containing the Tetrameric Ectodomain of Influenza Matrix Protein 2 and Flagellin Induce Heterosubtypic Protection in Mice

The ectodomain of matrix protein 2 (M2e) is highly conserved among influenza A viruses and can be a promising candidate antigen for a broadly cross-protective vaccine. In this study, a tetrameric M2e (tM2e) and a truncated form of flagellin (tFliC) were coincorporated into virus-like particles (VLPs...

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Detalhes bibliográficos
Main Authors: Wang, Li, Wang, Ying-Chun, Feng, Hao, Ahmed, Tamanna, Compans, Richard W., Wang, Bao-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745920/
https://ncbi.nlm.nih.gov/pubmed/23984396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/686549
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