Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections

There is great interest in passive transfer of broadly neutralizing antibodies (bnAbs) and engineered bispecific antibodies (Abs) for prevention of HIV-1 infections due to their in vitro neutralization breadth and potency against global isolates and long in vivo half-lives. We compared the potential...

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Vydáno v:PLoS Pathog
Hlavní autoři: Wagh, Kshitij, Seaman, Michael S., Zingg, Marshall, Fitzsimons, Tomas, Barouch, Dan H., Burton, Dennis R., Connors, Mark, Ho, David D., Mascola, John R., Nussenzweig, Michel C., Ravetch, Jeffrey, Gautam, Rajeev, Martin, Malcolm A., Montefiori, David C., Korber, Bette
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854441/
https://ncbi.nlm.nih.gov/pubmed/29505593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006860
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