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Optimization of Conformational Dynamics in an Epistatic Evolutionary Trajectory
The understanding of protein evolution depends on the ability to relate the impact of mutations on molecular traits to organismal fitness. Biological activity and robustness have been regarded as important features in shaping protein evolutionary landscapes. Conformational dynamics, which is essenti...
Shranjeno v:
| izdano v: | Mol Biol Evol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5854100/ https://ncbi.nlm.nih.gov/pubmed/26983555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msw052 |
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