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Optimization of Conformational Dynamics in an Epistatic Evolutionary Trajectory
The understanding of protein evolution depends on the ability to relate the impact of mutations on molecular traits to organismal fitness. Biological activity and robustness have been regarded as important features in shaping protein evolutionary landscapes. Conformational dynamics, which is essenti...
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| 出版年: | Mol Biol Evol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5854100/ https://ncbi.nlm.nih.gov/pubmed/26983555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msw052 |
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