Higher T-Cell Responses Induced by DNA/rAd5 HIV-1 Preventive Vaccine Are Associated With Lower HIV-1 Infection Risk in an Efficacy Trial

BACKGROUND. It is important to identify vaccine-induced immune responses that predict the preventative efficacy of a human immunodeficiency virus (HIV)–1 vaccine. We assessed T-cell response markers as correlates of risk in the HIV Vaccine Trials Network (HVTN) 505 HIV-1 vaccine efficacy trial. METH...

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Bibliografski detalji
Izdano u:J Infect Dis
Glavni autori: Janes, Holly E., Cohen, Kristen W., Frahm, Nicole, De Rosa, Stephen C., Sanchez, Brittany, Hural, John, Magaret, Craig A., Karuna, Shelly, Bentley, Carter, Gottardo, Raphael, Finak, Greg, Grove, Douglas, Shen, Mingchao, Graham, Barney S., Koup, Richard A., Mulligan, Mark J., Koblin, Beryl, Buchbinder, Susan P., Keefer, Michael C., Adams, Elizabeth, Anude, Chuka, Corey, Lawrence, Sobieszczyk, Magdalena, Hammer, Scott M., Gilbert, Peter B., McElrath, M. Juliana
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Major Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853653/
https://ncbi.nlm.nih.gov/pubmed/28199679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix086
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