Efficacy Trial of a DNA/rAd5 HIV-1 Preventive Vaccine

BACKGROUND: A safe and effective vaccine for the prevention of human immunodeficiency virus type 1 (HIV-1) infection is a global priority. We tested the efficacy of a DNA prime–recombinant adenovirus type 5 boost (DNA/rAd5) vaccine regimen in persons at increased risk for HIV-1 infection in the Unit...

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Hlavní autoři: Hammer, Scott M., Sobieszczyk, Magdalena E., Janes, Holly, Karuna, Shelly T., Mulligan, Mark J., Grove, Doug, Koblin, Beryl A., Buchbinder, Susan P., Keefer, Michael C., Tomaras, Georgia D., Frahm, Nicole, Hural, John, Anude, Chuka, Graham, Barney S., Enama, Mary E., Adams, Elizabeth, DeJesus, Edwin, Novak, Richard M., Frank, Ian, Bentley, Carter, Ramirez, Shelly, Fu, Rong, Koup, Richard A., Mascola, John R., Nabel, Gary J., Montefiori, David C., Kublin, James, McElrath, M. Juliana, Corey, Lawrence, Gilbert, Peter B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030634/
https://ncbi.nlm.nih.gov/pubmed/24099601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1310566
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