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Suppression of Ras-mediated tumorigenicity and metastasis through inhibition of the Met receptor tyrosine kinase

Mutations in the Ras family of GTP binding proteins represent one of the most frequently observed genetic alterations in human cancers. We and others have recently demonstrated that expression of Met, the tyrosine kinase receptor for hepatocyte growth factor/scatter factor (HGF/SF), is significantly...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Furge, Kyle A., Kiewlich, David, Le, Phuong, Vo, My Nga, Faure, Michel, Howlett, Anthony R., Lipson, Kenneth E., Woude, George F. Vande, Webb, Craig P.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2001
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC58533/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11535809/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.191067898
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