Suppression of Ras-mediated tumorigenicity and metastasis through inhibition of the Met receptor tyrosine kinase

Mutations in the Ras family of GTP binding proteins represent one of the most frequently observed genetic alterations in human cancers. We and others have recently demonstrated that expression of Met, the tyrosine kinase receptor for hepatocyte growth factor/scatter factor (HGF/SF), is significantly...

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Autori principali: Furge, Kyle A., Kiewlich, David, Le, Phuong, Vo, My Nga, Faure, Michel, Howlett, Anthony R., Lipson, Kenneth E., Woude, George F. Vande, Webb, Craig P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC58533/
https://ncbi.nlm.nih.gov/pubmed/11535809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191067898
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