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The HAND1 frameshift A126FS mutation does not cause hypoplastic left heart syndrome in mice

AIMS: To test if a human Hand1 frame shift mutation identified in human samples is causative of hypoplastic left heart syndrome (HLHS). METHODS AND RESULTS: HLHS is a poorly understood single ventricle congenital heart defect that affects two to three infants in every 10 000 live births. The aetiolo...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Firulli, Beth A, Toolan, Kevin P, Harkin, Jade, Millar, Hannah, Pineda, Santiago, Firulli, Anthony B
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852545/
https://ncbi.nlm.nih.gov/pubmed/29016838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvx166
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