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Hand factor ablation causes defective left ventricular chamber development and compromised adult cardiac function
Coordinated cardiomyocyte growth, differentiation, and morphogenesis are essential for heart formation. We demonstrate that the bHLH transcription factors Hand1 and Hand2 play critical regulatory roles for left ventricle (LV) cardiomyocyte proliferation and morphogenesis. Using an LV-specific Cre al...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5544250/ https://ncbi.nlm.nih.gov/pubmed/28732025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006922 |
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