Defective Hand1 phosphoregulation uncovers essential roles for Hand1 in limb morphogenesis

The morphogenesis of the vertebrate limbs is a complex process in which cell signaling and transcriptional regulation coordinate diverse structural adaptations in diverse species. In this study, we examine the consequences of altering Hand1 dimer choice regulation within developing vertebrate limbs....

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Bibliographic Details
Published in:Development
Main Authors: Firulli, Beth A., Milliar, Hannah, Toolan, Kevin P., Harkin, Jade, Fuchs, Robyn K., Robling, Alex G., Firulli, Anthony B.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536869/
https://ncbi.nlm.nih.gov/pubmed/28576769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.149963
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