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Hand1 phosphoregulation within the distal arch neural crest is essential for craniofacial morphogenesis

In this study we examine the consequences of altering Hand1 phosphoregulation in the developing neural crest cells (NCCs) of mice. Whereas Hand1 deletion in NCCs reveals a nonessential role for Hand1 in craniofacial development and embryonic survival, altering Hand1 phosphoregulation, and consequent...

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Détails bibliographiques
Auteurs principaux: Firulli, Beth A., Fuchs, Robyn K., Vincentz, Joshua W., Clouthier, David E., Firulli, Anthony B.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197675/
https://ncbi.nlm.nih.gov/pubmed/25053435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.107680
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