Hand1 phosphoregulation within the distal arch neural crest is essential for craniofacial morphogenesis

In this study we examine the consequences of altering Hand1 phosphoregulation in the developing neural crest cells (NCCs) of mice. Whereas Hand1 deletion in NCCs reveals a nonessential role for Hand1 in craniofacial development and embryonic survival, altering Hand1 phosphoregulation, and consequent...

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Autores principales: Firulli, Beth A., Fuchs, Robyn K., Vincentz, Joshua W., Clouthier, David E., Firulli, Anthony B.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists 2014
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197675/
https://ncbi.nlm.nih.gov/pubmed/25053435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.107680
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