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Atheroprone flow activates inflammation via endothelial ATP-dependent P2X7-p38 signalling

OBJECTIVE: Atherosclerosis is a focal disease occurring at arterial sites of disturbed blood flow that generates low oscillating shear stress. Endothelial inflammatory signalling is enhanced at sites of disturbed flow via mechanisms that are incompletely understood. The influence of disturbed flow o...

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Detalles Bibliográficos
Publicado en:Cardiovasc Res
Main Authors: Green, Jack P, Souilhol, Celine, Xanthis, Ioannis, Martinez-Campesino, Laura, Bowden, Neil P, Evans, Paul C, Wilson, Heather L
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852506/
https://ncbi.nlm.nih.gov/pubmed/29126223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvx213
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