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Atheroprone flow activates inflammation via endothelial ATP-dependent P2X7-p38 signalling

OBJECTIVE: Atherosclerosis is a focal disease occurring at arterial sites of disturbed blood flow that generates low oscillating shear stress. Endothelial inflammatory signalling is enhanced at sites of disturbed flow via mechanisms that are incompletely understood. The influence of disturbed flow o...

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Vydáno v:Cardiovasc Res
Hlavní autoři: Green, Jack P, Souilhol, Celine, Xanthis, Ioannis, Martinez-Campesino, Laura, Bowden, Neil P, Evans, Paul C, Wilson, Heather L
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852506/
https://ncbi.nlm.nih.gov/pubmed/29126223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvx213
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