Tuning the stereo-hindrance of a curcumin scaffold for the selective imaging of the soluble forms of amyloid beta species

Amyloid peptides and proteins are associated with the pathologies of numerous diseases. In the progression of a disease, amyloids exist in soluble and insoluble forms, which are the dominant species at different stages of the disease and they have different degrees of toxicity. However, differentiat...

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Udgivet i:Chem Sci
Main Authors: Li, Yuyan, Yang, Jian, Liu, Hongwu, Yang, Jing, Du, Lei, Feng, Haiwei, Tian, Yanli, Cao, Jianqin, Ran, Chongzhao
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2017
Fag:
Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851342/
https://ncbi.nlm.nih.gov/pubmed/29568434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc02050c
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