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The double-edged role of copper in the fate of amyloid beta in the presence of anti-oxidants

The biological fate of amyloid beta (Aβ) species is a fundamental question in Alzheimer’s disease (AD) pathogenesis. The competition between clearance and aggregation of Aβs is critical for the onset of AD. Copper has been widely considered to be an inducer of harmful crosslinking of Aβs, and an imp...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Yang, Jing, Zhang, Xueli, Zhu, Yiying, Lenczowski, Emily, Tian, Yanli, Yang, Jian, Zhang, Can, Hardt, Markus, Qiao, Chunhua, Tanzi, Rudolph E., Moore, Anna, Ye, Hui, Ran, Chongzhao
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627602/
https://ncbi.nlm.nih.gov/pubmed/28989646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01787a
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