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Bifunctional curcumin analogue for two-photon imaging and inhibiting crosslinking of amyloid beta in Alzheimer’s disease
In this report, we designed a highly bright bifunctional curcumin analogue CRANAD-28. In vivo two-photon imaging suggested that CRANAD-28 could penetrate the blood brain barrier (BBB) and label plaques and cerebral amyloid angiopathy (CAAs). We also demonstrated that this imaging probe could inhibit...
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| 發表在: | Chem Commun (Camb) |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4617557/ https://ncbi.nlm.nih.gov/pubmed/25134928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc03731f |
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