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Crown ethers attenuate aggregation of Amyloid beta of Alzheimer’s disease

The stagnant state of drug development for Alzheimer’s disease demands new approaches for seeking promising candidates. In this report, we reasoned that non-covalent modification of amyloid beta (Aβ) peptide by crown ethers could inhibit its aggregation. To specifically target Aβs, a conjugate of Pi...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Tian, Yanli, Zhang, Xueli, Li, Yuyan, Shoup, Timothy M., Teng, Xin, Elmaleh, David R., Moore, Anna, Ran, Chongzhao
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617529/
https://ncbi.nlm.nih.gov/pubmed/25372154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc06029f
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