Loading...
Probing Structural Changes among Analogous Inhibitor-Bound Forms of HIV-1 Protease and a Drug-Resistant Mutant in Solution by NMR
In the era of state-of-the-art inhibitor design and high-resolution structural studies, detection of significant but small protein structural differences in the inhibitor-bound forms is critical to further developing the inhibitor. Here, we probed differences in HIV-1 protease (PR) conformation amon...
Saved in:
| Published in: | Biochemistry |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2018
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5850901/ https://ncbi.nlm.nih.gov/pubmed/29457713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01238 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|