Carregant...

Probing Structural Changes among Analogous Inhibitor-Bound Forms of HIV-1 Protease and a Drug-Resistant Mutant in Solution by NMR

In the era of state-of-the-art inhibitor design and high-resolution structural studies, detection of significant but small protein structural differences in the inhibitor-bound forms is critical to further developing the inhibitor. Here, we probed differences in HIV-1 protease (PR) conformation amon...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Biochemistry
Autors principals: Khan, Shahid N, Persons, John D, Paulsen, Janet L., Guerrero, Michel, Schiffer, Celia A., Kurt-Yilmaz, Nese, Ishima, Rieko
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850901/
https://ncbi.nlm.nih.gov/pubmed/29457713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01238
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!