Transplantation of Allogeneic Pericytes Improves Myocardial Vascularization and Reduces Interstitial Fibrosis in a Swine Model of Reperfused Acute Myocardial Infarction

BACKGROUND: Transplantation of adventitial pericytes (APCs) promotes cardiac repair in murine models of myocardial infarction. The aim of present study was to confirm the benefit of APC therapy in a large animal model. METHODS AND RESULTS: We performed a blind, randomized, placebo‐controlled APC the...

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Udgivet i:J Am Heart Assoc
Main Authors: Alvino, Valeria Vincenza, Fernández‐Jiménez, Rodrigo, Rodriguez‐Arabaolaza, Iker, Slater, Sadie, Mangialardi, Giuseppe, Avolio, Elisa, Spencer, Helen, Culliford, Lucy, Hassan, Sakinah, Sueiro Ballesteros, Lorena, Herman, Andrew, Ayaon‐Albarrán, Ali, Galán‐Arriola, Carlos, Sánchez‐González, Javier, Hennessey, Helena, Delmege, Catherine, Ascione, Raimondo, Emanueli, Costanza, Angelini, Gianni Davide, Ibanez, Borja, Madeddu, Paolo
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850145/
https://ncbi.nlm.nih.gov/pubmed/29358198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.006727
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