Transplantation of Allogeneic Pericytes Improves Myocardial Vascularization and Reduces Interstitial Fibrosis in a Swine Model of Reperfused Acute Myocardial Infarction

BACKGROUND: Transplantation of adventitial pericytes (APCs) promotes cardiac repair in murine models of myocardial infarction. The aim of present study was to confirm the benefit of APC therapy in a large animal model. METHODS AND RESULTS: We performed a blind, randomized, placebo‐controlled APC the...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Alvino, Valeria Vincenza, Fernández‐Jiménez, Rodrigo, Rodriguez‐Arabaolaza, Iker, Slater, Sadie, Mangialardi, Giuseppe, Avolio, Elisa, Spencer, Helen, Culliford, Lucy, Hassan, Sakinah, Sueiro Ballesteros, Lorena, Herman, Andrew, Ayaon‐Albarrán, Ali, Galán‐Arriola, Carlos, Sánchez‐González, Javier, Hennessey, Helena, Delmege, Catherine, Ascione, Raimondo, Emanueli, Costanza, Angelini, Gianni Davide, Ibanez, Borja, Madeddu, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850145/
https://ncbi.nlm.nih.gov/pubmed/29358198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.006727
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