The adipokine leptin modulates adventitial pericyte functions by autocrine and paracrine signalling

Transplantation of adventitial pericytes (APCs) improves recovery from tissue ischemia in preclinical animal models by still unknown mechanisms. This study investigates the role of the adipokine leptin (LEP) in the regulation of human APC biological functions. Transcriptomic analysis of APCs showed...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Riu, Federica, Slater, Sadie C., Garcia, Eva Jover, Rodriguez-Arabaolaza, Iker, Alvino, Valeria, Avolio, Elisa, Mangialardi, Giuseppe, Cordaro, Andrea, Satchell, Simon, Zebele, Carlo, Caporali, Andrea, Angelini, Gianni, Madeddu, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511138/
https://ncbi.nlm.nih.gov/pubmed/28710369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05868-y
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