Transplantation of Allogeneic Pericytes Improves Myocardial Vascularization and Reduces Interstitial Fibrosis in a Swine Model of Reperfused Acute Myocardial Infarction

BACKGROUND: Transplantation of adventitial pericytes (APCs) promotes cardiac repair in murine models of myocardial infarction. The aim of present study was to confirm the benefit of APC therapy in a large animal model. METHODS AND RESULTS: We performed a blind, randomized, placebo‐controlled APC the...

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Pubblicato in:J Am Heart Assoc
Autori principali: Alvino, Valeria Vincenza, Fernández‐Jiménez, Rodrigo, Rodriguez‐Arabaolaza, Iker, Slater, Sadie, Mangialardi, Giuseppe, Avolio, Elisa, Spencer, Helen, Culliford, Lucy, Hassan, Sakinah, Sueiro Ballesteros, Lorena, Herman, Andrew, Ayaon‐Albarrán, Ali, Galán‐Arriola, Carlos, Sánchez‐González, Javier, Hennessey, Helena, Delmege, Catherine, Ascione, Raimondo, Emanueli, Costanza, Angelini, Gianni Davide, Ibanez, Borja, Madeddu, Paolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850145/
https://ncbi.nlm.nih.gov/pubmed/29358198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.006727
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