The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated‐recombinant arginase I BCT‐100

Arginine is a semi‐essential amino acid that plays a key role in cell survival and proliferation in normal and malignant cells. BCT‐100, a pegylated (PEG) recombinant human arginase, can deplete arginine and starve malignant cells of the amino acid. Acute lymphoblastic leukemia (ALL) is the most com...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: De Santo, Carmela, Booth, Sarah, Vardon, Ashley, Cousins, Antony, Tubb, Vanessa, Perry, Tracey, Noyvert, Boris, Beggs, Andrew, Ng, Margaret, Halsey, Christina, Kearns, Pamela, Cheng, Paul, Mussai, Francis
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Cancer Therapy and Prevention
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849425/
https://ncbi.nlm.nih.gov/pubmed/29168171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31170
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados