Targeting the arginine metabolic brake enhances immunotherapy for leukaemia

Therapeutic approaches which aim to target Acute Myeloid Leukaemia through enhancement of patients’ immune responses have demonstrated limited efficacy to date, despite encouraging preclinical data. Examination of AML patients treated with azacitidine (AZA) and vorinostat (VOR) in a Phase II trial,...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Mussai, Francis, Wheat, Rachel, Sarrou, Evgenia, Booth, Sarah, Stavrou, Victoria, Fultang, Livingstone, Perry, Tracey, Kearns, Pamela, Cheng, Paul, Keeshan, Karen, Craddock, Charles, De Santo, Carmela
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Tumor Immunology and Microenvironment
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767531/
https://ncbi.nlm.nih.gov/pubmed/30485425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.32028
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