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Chemoenzymatic synthesis of heparan sulfate and heparin oligosaccharides and NMR analysis: paving the way to a diverse library for glycobiologists

Heparan sulfate (HS) is a member of the glycosaminoglycans (GAG) family that plays essential roles in biological processes from animal sources. Heparin, a highly sulfated form of HS, is widely used as anticoagulant drug worldwide. The high diversity and complexity of HS and heparin represent a roadb...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Chem Sci
Main Authors: Zhang, Xing, Pagadala, Vijayakanth, Jester, Hannah M., Lim, Andrew M., Pham, Truong Quang, Goulas, Anna Marie P., Liu, Jian, Linhardt, Robert J.
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849142/
https://ncbi.nlm.nih.gov/pubmed/29568440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03541a
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