3′ UTR lengthening as a novel mechanism in regulating cellular senescence

Cellular senescence has been viewed as a tumor suppression mechanism and also as a contributor to individual aging. Widespread shortening of 3′ untranslated regions (3′ UTRs) in messenger RNAs (mRNAs) by alternative polyadenylation (APA) has recently been discovered in cancer cells. However, the rol...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Genome Res
Päätekijät: Chen, Meng, Lyu, Guoliang, Han, Miao, Nie, Hongbo, Shen, Ting, Chen, Wei, Niu, Yichi, Song, Yifan, Li, Xueping, Li, Huan, Chen, Xinyu, Wang, Ziyue, Xia, Zheng, Li, Wei, Tian, Xiao-Li, Ding, Chen, Gu, Jun, Zheng, Yufang, Liu, Xinhua, Hu, Jinfeng, Wei, Gang, Tao, Wei, Ni, Ting
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2018
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848608/
https://ncbi.nlm.nih.gov/pubmed/29440281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.224451.117
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