The D113N mutation in the RING E3 ubiquitin protein ligase gene is not associated with ex vivo susceptibility to common anti-malarial drugs in African Plasmodium falciparum isolates

BACKGROUND: Plasmodium falciparum resistance to artemisinin-based combination therapy has emerged and spread in Southeast Asia. In areas where artemisinin resistance is emerging, the efficacy of combination is now based on partner drugs. In this context, the identification of novel markers of resist...

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Vydáno v:Malar J
Hlavní autoři: Gendrot, Mathieu, Foguim, Francis Tsombeng, Robert, Marie Gladys, Amalvict, Rémy, Mosnier, Joel, Benoit, Nicolas, Madamet, Marylin, Pradines, Bruno
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848522/
https://ncbi.nlm.nih.gov/pubmed/29530046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2252-2
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