The D113N mutation in the RING E3 ubiquitin protein ligase gene is not associated with ex vivo susceptibility to common anti-malarial drugs in African Plasmodium falciparum isolates

BACKGROUND: Plasmodium falciparum resistance to artemisinin-based combination therapy has emerged and spread in Southeast Asia. In areas where artemisinin resistance is emerging, the efficacy of combination is now based on partner drugs. In this context, the identification of novel markers of resist...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Gendrot, Mathieu, Foguim, Francis Tsombeng, Robert, Marie Gladys, Amalvict, Rémy, Mosnier, Joel, Benoit, Nicolas, Madamet, Marylin, Pradines, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848522/
https://ncbi.nlm.nih.gov/pubmed/29530046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2252-2
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