Absence of Association between Polymorphisms in the RING E3 Ubiquitin Protein Ligase Gene and Ex Vivo Susceptibility to Conventional Antimalarial Drugs in Plasmodium falciparum Isolates from Dakar, Senegal

The RING E3 ubiquitin protein ligase is crucial for facilitating the transfer of ubiquitin. The only polymorphism identified in the E3 ubiquitin protein ligase gene was the D113N mutation (62.5%) but was not significantly associated with the 50% inhibitory concentration (IC(50)) of conventional anti...

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Foilsithe in:Antimicrob Agents Chemother
Main Authors: Gendrot, Mathieu, Fall, Bécaye, Madamet, Marylin, Fall, Mansour, Wade, Khalifa Ababacar, Amalvict, Rémy, Nakoulima, Aminata, Benoit, Nicolas, Diawara, Silman, Diémé, Yaya, Diatta, Bakary, Wade, Boubacar, Pradines, Bruno
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2016
Ábhair:
Mechanisms of Resistance
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958203/
https://ncbi.nlm.nih.gov/pubmed/27185795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03105-15
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