Absence of Association between Polymorphisms in the RING E3 Ubiquitin Protein Ligase Gene and Ex Vivo Susceptibility to Conventional Antimalarial Drugs in Plasmodium falciparum Isolates from Dakar, Senegal

The RING E3 ubiquitin protein ligase is crucial for facilitating the transfer of ubiquitin. The only polymorphism identified in the E3 ubiquitin protein ligase gene was the D113N mutation (62.5%) but was not significantly associated with the 50% inhibitory concentration (IC(50)) of conventional anti...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Antimicrob Agents Chemother
المؤلفون الرئيسيون: Gendrot, Mathieu, Fall, Bécaye, Madamet, Marylin, Fall, Mansour, Wade, Khalifa Ababacar, Amalvict, Rémy, Nakoulima, Aminata, Benoit, Nicolas, Diawara, Silman, Diémé, Yaya, Diatta, Bakary, Wade, Boubacar, Pradines, Bruno
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology 2016
الموضوعات:
Mechanisms of Resistance
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958203/
https://ncbi.nlm.nih.gov/pubmed/27185795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03105-15
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