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Association between Polymorphisms in the Pfmdr6 Gene and Ex Vivo Susceptibility to Quinine in Plasmodium falciparum Parasites from Dakar, Senegal

Polymorphisms and the overexpression of transporter genes, especially of the ATP-binding cassette superfamily, have been involved in antimalarial drug resistance. The objective of this study was to use 77 Senegalese Plasmodium falciparum isolates to evaluate the association between the number of Asn...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Gendrot, Mathieu, Diawara, Silman, Madamet, Marylin, Kounta, Mame Bou, Briolant, Sébastien, Wade, Khalifa Ababacar, Fall, Mansour, Benoit, Nicolas, Nakoulima, Aminata, Amalvict, Rémy, Diémé, Yaya, Fall, Bécaye, Wade, Boubacar, Diatta, Bakary, Pradines, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328570/
https://ncbi.nlm.nih.gov/pubmed/28052850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01183-16
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