Association between Polymorphisms in the Pfmdr6 Gene and Ex Vivo Susceptibility to Quinine in Plasmodium falciparum Parasites from Dakar, Senegal

Polymorphisms and the overexpression of transporter genes, especially of the ATP-binding cassette superfamily, have been involved in antimalarial drug resistance. The objective of this study was to use 77 Senegalese Plasmodium falciparum isolates to evaluate the association between the number of Asn...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Gendrot, Mathieu, Diawara, Silman, Madamet, Marylin, Kounta, Mame Bou, Briolant, Sébastien, Wade, Khalifa Ababacar, Fall, Mansour, Benoit, Nicolas, Nakoulima, Aminata, Amalvict, Rémy, Diémé, Yaya, Fall, Bécaye, Wade, Boubacar, Diatta, Bakary, Pradines, Bruno
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328570/
https://ncbi.nlm.nih.gov/pubmed/28052850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01183-16
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