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Strategies to Improve the Clinical Utility of Saporin-Based Targeted Toxins

Plant Ribosome-inactivating proteins (RIPs) including the type I RIP Saporin have been used for the construction of Immunotoxins (ITxs) obtained via chemical conjugation of the toxic domain to whole antibodies or by generating genetic fusions to antibody fragments/targeting domains able to direct th...

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Dades bibliogràfiques
Publicat a:Toxins (Basel)
Autors principals: Giansanti, Francesco, Flavell, David J., Angelucci, Francesco, Fabbrini, Maria Serena, Ippoliti, Rodolfo
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848183/
https://ncbi.nlm.nih.gov/pubmed/29438358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10020082
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