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Strategies to Improve the Clinical Utility of Saporin-Based Targeted Toxins
Plant Ribosome-inactivating proteins (RIPs) including the type I RIP Saporin have been used for the construction of Immunotoxins (ITxs) obtained via chemical conjugation of the toxic domain to whole antibodies or by generating genetic fusions to antibody fragments/targeting domains able to direct th...
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| Publicado en: | Toxins (Basel) |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5848183/ https://ncbi.nlm.nih.gov/pubmed/29438358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10020082 |
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