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An Evolutionary/Biochemical Connection between Promoter- and Primer-Dependent Polymerases Revealed by Systematic Evolution of Ligands by Exponential Enrichment

DNA polymerases (DNAPs) recognize 3′ recessed termini on duplex DNA and carry out nucleotide catalysis. Unlike promoter-specific RNA polymerases (RNAPs), no sequence specificity is required for binding or initiation of catalysis. Despite this, previous results indicate that viral reverse transcripta...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Main Authors: Fenstermacher, Katherine J., Achuthan, Vasudevan, Schneider, Thomas D., DeStefano, Jeffrey J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847653/
https://ncbi.nlm.nih.gov/pubmed/29339418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00579-17
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