Structural model of human dUTPase in complex with a novel proteinaceous inhibitor

Human deoxyuridine 5′-triphosphate nucleotidohydrolase (dUTPase), essential for DNA integrity, acts as a survival factor for tumor cells and is a target for cancer chemotherapy. Here we report that the Staphylococcal repressor protein Stl(SaPIBov1) (Stl) forms strong complex with human dUTPase. Func...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Nyíri, Kinga, Mertens, Haydyn D. T., Tihanyi, Borbála, Nagy, Gergely N., Kőhegyi, Bianka, Matejka, Judit, Harris, Matthew J., Szabó, Judit E., Papp-Kádár, Veronika, Németh-Pongrácz, Veronika, Ozohanics, Olivér, Vékey, Károly, Svergun, Dmitri I., Borysik, Antoni J., Vértessy, Beáta G.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847570/
https://ncbi.nlm.nih.gov/pubmed/29531348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22145-8
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料