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HDX and Native Mass Spectrometry Reveals the Different Structural Basis for Interaction of the Staphylococcal Pathogenicity Island Repressor Stl with Dimeric and Trimeric Phage dUTPases

The dUTPase enzyme family plays an essential role in maintaining the genome integrity and are represented by two distinct classes of proteins; the β-pleated homotrimeric and the all-α homodimeric dUTPases. Representatives of both trimeric and dimeric dUTPases are encoded by Staphylococcus aureus pha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biomolecules
Hauptverfasser: Nyíri, Kinga, Harris, Matthew J., Matejka, Judit, Ozohanics, Olivér, Vékey, Károly, Borysik, Antoni J., Vértessy, Beáta G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770826/
https://ncbi.nlm.nih.gov/pubmed/31540005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9090488
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