Highly potent dUTPase inhibition by a bacterial repressor protein reveals a novel mechanism for gene expression control

Transfer of phage-related pathogenicity islands of Staphylococcus aureus (SaPI-s) was recently reported to be activated by helper phage dUTPases. This is a novel function for dUTPases otherwise involved in preservation of genomic integrity by sanitizing the dNTP pool. Here we investigated the molecu...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Szabó, Judit E., Németh, Veronika, Papp-Kádár, Veronika, Nyíri, Kinga, Leveles, Ibolya, Bendes, Ábris Á., Zagyva, Imre, Róna, Gergely, Pálinkás, Hajnalka L., Besztercei, Balázs, Ozohanics, Olivér, Vékey, Károly, Liliom, Károly, Tóth, Judit, Vértessy, Beáta G.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Gene regulation, Chromatin and Epigenetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231751/
https://ncbi.nlm.nih.gov/pubmed/25274731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku882
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