HPMA-Copolymer Nanocarrier Targets Tumor-Associated Macrophages in Primary and Metastatic Breast Cancer

Polymeric nanocarriers such as N-(2-hydroxypropyl) methacrylamide (HPMA) copolymers deliver drugs to solid tumors and avoid the systemic toxicity of conventional chemotherapy. Because HPMA copolymers can target sites of inflammation and accumulate within innate immune cells, we hypothesized that HPM...

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Publicado en:Mol Cancer Ther
Main Authors: Zimel, Melissa N., Horowitz, Chloe B., Rajasekhar, Vinagolu K., Christ, Alexander B., Wei, Xin, Wu, Jianbo, Wojnarowicz, Paulina M., Wang, Dong, Goldring, Steven R., Purdue, P. Edward, Healey, John H.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847372/
https://ncbi.nlm.nih.gov/pubmed/28830983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0995
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