Targetable HPMA Copolymer–Aminohexylgeldanamycin Conjugates for Prostate Cancer Therapy

PURPOSE: This study focuses on the synthesis and characterization of N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer–cyclo-RGD (Arg-Gly-Asp) conjugates for delivery of geldanamycin to prostate tumors. MATERIALS AND METHODS: HPMA copolymers containing aminohexylgeldanamycin (AH-GDM) with and witho...

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Detalhes bibliográficos
Main Authors: Borgman, Mark P., Ray, Abhijit, Kolhatkar, Rohit B., Sausville, Edward A., Burger, Angelika M., Ghandehari, Hamidreza
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952876/
https://ncbi.nlm.nih.gov/pubmed/19225872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-9851-0
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