Comparison of Active and Passive Targeting of Docetaxel for Prostate Cancer Therapy by HPMA copolymer-RGDfK Conjugates

N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-docetaxel-RGDfK conjugate was synthesized, characterized, and evaluated in vitro and in vivo in comparison with untargeted low and high molecular weight HPMA copolymer-docetaxel conjugates. The targeted conjugate was designed to have a hydrodynamic...

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Bibliografiske detaljer
Main Authors: Ray, Abhijit, Larson, Nate, Pike, Daniel B., Grüner, Michele, Naik, Sachin, Bauer, Hillevi, Malugin, Alexander, Greish, Khaled, Ghandehari, Hamidreza
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178325/
https://ncbi.nlm.nih.gov/pubmed/21599008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100402n
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