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Allosteric mechanism of the V. vulnificus adenine riboswitch resolved by four-dimensional chemical mapping

The structural interconversions that mediate the gene regulatory functions of RNA molecules may be different from classic models of allostery, but the relevant structural correlations have remained elusive in even intensively studied systems. Here, we present a four-dimensional expansion of chemical...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Tian, Siqi, Kladwang, Wipapat, Das, Rhiju
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847336/
https://ncbi.nlm.nih.gov/pubmed/29446752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29602
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