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Allosteric mechanism of the V. vulnificus adenine riboswitch resolved by four-dimensional chemical mapping

The structural interconversions that mediate the gene regulatory functions of RNA molecules may be different from classic models of allostery, but the relevant structural correlations have remained elusive in even intensively studied systems. Here, we present a four-dimensional expansion of chemical...

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Foilsithe in:eLife
Main Authors: Tian, Siqi, Kladwang, Wipapat, Das, Rhiju
Formáid: Artigo
Teanga:Inglês
Foilsithe: eLife Sciences Publications, Ltd 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847336/
https://ncbi.nlm.nih.gov/pubmed/29446752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29602
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