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Allosteric mechanism of the V. vulnificus adenine riboswitch resolved by four-dimensional chemical mapping

The structural interconversions that mediate the gene regulatory functions of RNA molecules may be different from classic models of allostery, but the relevant structural correlations have remained elusive in even intensively studied systems. Here, we present a four-dimensional expansion of chemical...

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Pubblicato in:eLife
Autori principali: Tian, Siqi, Kladwang, Wipapat, Das, Rhiju
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847336/
https://ncbi.nlm.nih.gov/pubmed/29446752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29602
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